A Missing Step in Glycogen Synthesis

Assessment analytics: The missing step

Assessment is a central element of the learning process; it defines what students consider important and measures their personal achievements across all phases of professional development. It gives institutions a valuable feedback about the success of realizing program goals and institution objectives.1 E-assessments are special types of assessments that use technology for management or deliver...

Information transfer--the missing step.

Allosteric regulation of glycogen synthase controls glycogen synthesis in muscle.

Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. The relative importance of these two regulatory mechanisms in controlling GS is not established, mainly due to the complex interplay between multiple phosphorylation sites and allosteric effecto...

Glycogen synthesis in human gastrocnemius muscle is not representative of whole-body muscle glycogen synthesis.

The introduction of 13C magnetic resonance spectroscopy (MRS) has enabled noninvasive measurement of muscle glycogen synthesis in humans. Conclusions based on measurements by the MRS technique assume that glucose metabolism in gastrocnemius muscle is representative for all skeletal muscles and thus can be extrapolated to whole-body muscle glucose metabolism. An alternative method to assess whol...

Mechanism Underlying Hepatic Glycogen Synthesis